Imvexxy is a prescription vaginal estrogen insert used to treat moderate to severe dyspareunia (pain during sexual intercourse), a symptom of vulvar and vaginal atrophy (VVA), due to menopause. It contains the active ingredient estradiol, which is a form of estrogen.
As women go through menopause, their bodies produce less estrogen. This drop in estrogen levels causes changes in the vagina that can lead to symptoms like VVA. Using an estrogen product like Imvexxy helps relieve these symptoms by replacing the estrogen the body is no longer making at adequate levels.
Key points about Imvexxy and hormone therapy:
- Imvexxy is considered a localized estrogen therapy, not a systemic hormone replacement therapy.
- The estradiol in Imvexxy is delivered directly to the vaginal tissue and stays concentrated there. Very little is absorbed into the bloodstream.
- It is used specifically to treat moderate to severe dyspareunia related to VVA due to menopause.
- It has not been studied as a treatment for other menopausal symptoms or conditions.
- Treatment is localized to vaginal tissue only. Imvexxy does not treat hot flashes, night sweats, or other systemic manifestations of menopause or impact circulating sex hormone concentrations.
Imvexxy usage and administration:
- Comes as a digitally inserted vaginal insert that dissolves to release estradiol.
- Usual dosage is one insert intravaginally once daily for 2 weeks, then twice weekly.
- Dosing may be individualized based on clinical response.
- Effects on dyspareunia and VVA may take up to 8–12 weeks to see. Treatment is considered long-term if effective.
- Common side effects include headache, nasal congestion/runny nose, bronchitis, and endometrial thickening.
So in summary,
Imvexxy is not a systemic hormone replacement therapy. It is a
localized vaginal estrogen treatment used specifically to treat moderate to severe dyspareunia related to VVA caused by menopause. The estradiol stays concentrated in the vaginal tissue to provide relief of symptoms rather than circulating throughout the body like traditional hormone therapy.
If you're experiencing vaginal or vulvar symptoms related to menopause, speak to your healthcare provider about whether Imvexxy may be an appropriate treatment option for you.
The hormone restoration specialists at Hormone Harmony have years of experience developing individualized estrogen therapy plans to help relieve VVA symptoms for women. Reach out today to learn more and schedule a consultation to discuss Imvexxy or other vaginal estrogen products that may meet your needs.
